Thrombolytic therapy, infarct vessel patency and late potentials: Can the arrhythmic substrate be altered?
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چکیده
منابع مشابه
Thrombolytic therapy, infarct vessel patency and late potentials: can the arrhythmic substrate be altered?
Historical background. More than 15 years have passed since localized epicardial electrical signals beyond ventricular activation were recorded in dogs with ventricular arrhythmias after experimental myocardial infarction (I) and subsequently termed "late potentials." These observations became the basis for catheter and intraoperative electrical mapping in humans with sustained ventricular tach...
متن کاملImproved early infarct-related vessel patency after thrombolytic therapy.
The major goal of reperfusion strategies in patients with acute myocardial infarction is to achieve patency of the infarct-related artery . Improvement in ventricular function and survival are related to initial and continued potency of this artery . The greater initial patency of the infarct-related artery after intravenous recombinant tissue-type plasminogen activator (r(-PA) compared with th...
متن کاملThrombolytic therapy reduces the incidence of left ventricular thrombus after anterior myocardial infarction. Relationship to vessel patency and infarct size.
BACKGROUND Controversial evidence exists as to whether thrombolytic therapy reduces the incidence of left ventricular thrombus in acute myocardial infarction and, if so, how this relates to successful reperfusion. METHODS Four hundred and eighteen consecutive patients underwent echocardiography and coronary angiography within 3 weeks of an acute myocardial infarction. A dyssynergic score was ...
متن کاملLong-term prognostic importance of patency of the infarct-related coronary artery after thrombolytic therapy for acute myocardial infarction.
BACKGROUND After thrombolytic therapy, long-term patency of the infarct-related artery may reduce arrhythmias, limit ventricular dilatation, and provide collaterals to another infarct zone if further infarction occurs. However, independent long-term prognostic value of infarct artery patency has not been shown. METHODS AND RESULTS We followed 312 patients with first myocardial infarction trea...
متن کاملIndependent impact of thrombolytic therapy and vessel patency on left ventricular dilation after myocardial infarction. Serial echocardiographic follow-up.
BACKGROUND It has been shown that successful reperfusion of the infarct-related artery by thrombolysis can prevent left ventricular dilation after acute myocardial infarction; these beneficial effects were detected from several days to several months after infarction. To date, however, no study has shown that these effects can be demonstrated within hours after the onset of infarction. Furtherm...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1990
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(10)80013-0